Thetg
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Thetg
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Webivevolumesof100,200,400,600and800mm3 fromthefirsttreatmentday.TheTG-50 was calculated by logit analysis. Growth delay time (GDT) is the time (days) difference between the TG-50 (800mm3) of treatedtumours andthat of control tumours;namely,GDT¼ TG-50(800mm3)(treated) TG-50(800mm3)(control). WebTheTg.ACtransgenicmouse lineisamong the alternative shortterminvivoassays for assessing the carcinogenic po-tential of chemicals that were evaluated by the Alternatives for Carcinogenicity Testing(ACT)Committee of the ILSI Health and Environmental Sciences Institute(HESI)(19). The Tg.AC mouse is one of several transgenic models pos-
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WebYears had passed since the day he rode away on Epona, taking any fond childhood memories I could manage to salvage from my muddled memories into the uncertainty of … Webshow an increase with time, theTG had an estimated maximum (E max) of 27% after 4 hours. The E max for TG is estimated with some uncertainty. As shown inTable 1, the delay betweenT max and E max varies con-siderably among the 8 drugs or the drug combination: 1–2h (zolmitriptan), 2½ h (sumatriptan), 3½ h (ibuprofen), 4 h (diclofenac,
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