WebApr 23, 2024 · Wolbachia are maternally inherited, intracellular bacteria at the forefront of vector control efforts to curb arbovirus transmission. In international field trials, the cytoplasmic incompatibility (CI) drive system of wMel Wolbachia is deployed to replace target vector populations, whereby a Wolbachia-induced modification of the sperm … WebWolbachia are maternally inherited bacteria that induce cytoplasmic incompatibility in mosquitoes, and are able to use these patterns of sterility to spread themselves through populations. For this reason they have been proposed as a gene drive system for mosquito genetic replacement, as well as for the reduction of population size or for modulating …
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WebFinally, Wolbachia can induce cytoplasmic incompatibility phenomena: a non-carrier female fertilized by a carrier male will not produce descendants. A carrier male can … WebMar 28, 2024 · In cytoplasmic incompatibility (CI), a sterility syndrome originally discovered in the mosquito Culex pipiens, uninfected eggs fertilized by sperm from infected males are selectively killed during embryo development following the abortive segregation of paternal chromosomes in the zygote. cicely hunt
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WebMar 28, 2024 · The Wolbachia cytoplasmic incompatibility factors are encoded by related two-gene operons ( Figure 1 A). The downstream gene usually encodes a deubiquitylase that cleaves ubiquitin from substrate proteins (cytoplasmic incompatibility-inducing deubiquitylase, CidB) or a DNA-cleaving enzyme (cytoplasmic incompatibility-inducing … WebJul 22, 2024 · The reproductive alterations caused by Wolbachia include feminization, parthenogenesis, male killing and cytoplasmic incompatibility (CI), among which CI is the most common. CI leads to embryonic lethality when Wolbachia-infected males mate with uninfected females or those infected with an incompatible strain. WebMar 25, 2024 · Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue Crystal Structures of Wolbachia CidA and CidB Reveal Determinants of Bacteria-induced Cytoplasmic Incompatibility and Rescue Authors cicely hunter