WebApr 14, 2024 · Since HK-2-cells-generated-Abs, both by cisplatin or upon UV light exposure, can induce apoptosis in HK-2 cells, the purpose of this work was to study their metabolome and therein find the molecular features which help us to unravel the mechanisms of that phenomenon. WebCisplatin is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This …
Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to
WebCisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis. 1 It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA binding. 2 Cisplatin halts the cell … WebAug 6, 2015 · A yellow/blue fluorescence intensity ratio of 0.98 was calculated for cells treated only with cisplatin; however, the fluorescence ratio of N-acetylcysteine (NAC) (10 μM) and cisplatin co-treated cells decreased from 0.98 to 0.79 because mitochondrial ROS were scavenged. (D) Mitochondrial fragmentation caused by cisplatin was also reduced … dallas warriors hockey
Cisplatin - The Penicillin of Cancer
WebSep 1, 2024 · Cisplatin for injection, USP, a platinum-based drug for intravenous use, is … WebCisplatin is a chemotherapy drug. You might have it as a treatment for a number of … WebFeb 16, 2024 · What is cisplatin? Cisplatin is used together with other cancer drugs to … bird and mammal evolution